Proliferation Monitoring, Lesson 1: Basics of the Cell Cycle

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Lesson 1 of the proliferation course reviews the basic concepts of cell cycle biology, setting the stage for the more specific methods and applications discussed in Lessons 2 and 3. Topics discussed include:

  • Phases of the cell cycle and molecular events associated with each.
  • Cell cycle checkpoints and regulators (cyclins and cyclin dependent kinases).
  • The relationship between the cell cycle phase distribution of a sample and DNA content histogram.
  • The use of DNA content histograms in combination with metabolic labeling or cellular synchronization to determine kinetics of progression through the different cell cycle phases.



Kylie M. Price
Hugh Green Cytometry Core Facility
Malaghan Institute of Medical Research
Wellington, New Zealand


Katharine A. (Kathy) Muirhead
SciGro Inc., Midwest Office
Middleton, Wisconsin, USA


Paul K. Wallace
Department of Flow and Image Cytometry
Roswell Park Cancer Institute
Buffalo, New York, USA

CMLE Credit: 1.0


Proliferation Monitoring, Lesson 1: Basics of the Cell Cycle
Begin self-paced component package.
Begin self-paced component package. Online, self-paced course presented by Kylie Price, Katherine (Kathy) Muirhead, and Paul Wallace
Traducción – Roxana del Rio-Guerra/Diana Bonilla/Lourdes Arriaga Pizano/Alfonso Blanco
Open to download resource.
Open to download resource.
CMLE Evaluation Form
11 Questions
11 Questions CMLE Evaluation Form
Completion Credit
1.00 CMLE credit  |  Certificate available
1.00 CMLE credit  |  Certificate available