Proliferation Monitoring, Lesson 1: Basics of the Cell Cycle

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Lesson 1 of the proliferation course reviews the basic concepts of cell cycle biology, setting the stage for the more specific methods and applications discussed in Lessons 2 and 3. Topics discussed include:

  • Phases of the cell cycle and molecular events associated with each.
  • Cell cycle checkpoints and regulators (cyclins and cyclin dependent kinases).
  • The relationship between the cell cycle phase distribution of a sample and DNA content histogram.
  • The use of DNA content histograms in combination with metabolic labeling or cellular synchronization to determine kinetics of progression through the different cell cycle phases.

Authors:

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Kylie M. Price
Hugh Green Cytometry Core Facility
Malaghan Institute of Medical Research
Wellington, New Zealand

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Katharine A. (Kathy) Muirhead
SciGro Inc., Midwest Office
Middleton, Wisconsin, USA

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Paul K. Wallace
Department of Flow and Image Cytometry
Roswell Park Cancer Institute
Buffalo, New York, USA

CMLE Credit: 1.0

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Proliferation Monitoring, Lesson 1: Basics of the Cell Cycle
Begin self-paced component package.
Begin self-paced component package. Online, self-paced course presented by Kylie Price, Katherine (Kathy) Muirhead, and Paul Wallace
Traducción – Roxana del Rio-Guerra/Diana Bonilla/Lourdes Arriaga Pizano/Alfonso Blanco
Open to download resource.
Open to download resource.
CMLE Evaluation Form
11 Questions
11 Questions CMLE Evaluation Form
Completion Credit
1.00 CMLE credit  |  Certificate available
1.00 CMLE credit  |  Certificate available